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Events reported upon discontinuation of treatment with immediate-release paroxetine hydrochloride in the pediatric clinical trials that included a taper phase regimen, which occurred in at least 2 of patients who received immediate-release paroxetine hydrochloride and which occurred at a rate at least twice that of placebo, were emotional lability including suicidal ideation, suicide attempt, mood changes, and tearfulness , nervousness, dizziness, nausea, and abdominal pain see discontinuation of treatment with paroxetine hydrochloride controlled-release tablets .
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The study is now again in the news, as a new reanalysis of the its original data including about 77,000 pages of formerly inaccessible patient records shows that paxil was neither effective nor safe.
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Patients receiving continued remeron treatment experienced significantly lower relapse rates over the subsequent 40 weeks compared to those receiving placebo.
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